BDBM50173918 CHEMBL3809916

SMILES NC(=O)c1ccc2n([C@@H]3CCC[C@@H](C3)NC(=O)c3ccc(s3)C#N)c(nc2c1)-c1ccccn1

InChI Key InChIKey=FPWMCCRNEFWPIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173918   

LigandPNGBDBM50173918(CHEMBL3809916)
Affinity DataIC50: 251nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed
LigandPNGBDBM50173918(CHEMBL3809916)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2017
Entry Details Article
PubMed