BDBM50173941 5'N-(3-pyridylmethyl)-(2'R)-spiro[4-azabicyclo[2.2.2]octane-2,2'-furo[2,3-b]pyridine]-5'-amine::CHEMBL193329

SMILES C(Nc1cnc2O[C@@]3(Cc2c1)CN1CCC3CC1)c1cccnc1

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173941   

LigandPNGBDBM50173941(5'N-(3-pyridylmethyl)-(2'R)-spiro[4-azabicyclo[2.2...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173941(5'N-(3-pyridylmethyl)-(2'R)-spiro[4-azabicyclo[2.2...)
Affinity DataKi:  2.23E+3nMAssay Description:Binding affinity for human 5-hydroxytryptamine 3 serotonin membrane receptor using [3H]GR-65630More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed