BDBM50174236 (R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenylacetamido)methyl)cyclohexyl)piperazin-1-yl)propan-2-yl)-3,3-dimethylbutanamide::CHEMBL198723

SMILES CC(C)(C)CC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNC(=O)Cc2ccccc2)CCCCC1

InChI Key InChIKey=PAAHGURMBRUYHB-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174236   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174236((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataEC50:  570nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174236((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  750nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed