BDBM50174334 CHEMBL3809529

SMILES COc1ccc(\C=C\C(=O)c2ccc(Nc3nc(nc4ccccc34)-c3ccc(OC)c(OC)c3)cc2)cc1OC

InChI Key InChIKey=UELXDXUOBOULEV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174334   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50174334(CHEMBL3809529)Copy SMILESCopy InChI

Affinity DataIC50: 190nMAssay Description:Inhibition of human C-terminal GFP-tagged ABCG2 expressed in MDCK2 cells using pheophorbide A as substrate preincubated for 20 mins followed by subst...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/12/2017
Entry Details Article
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TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50174334(CHEMBL3809529)Copy SMILESCopy InChI

Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of ABCB1 in human A2780/ADR cells incubated for 30 mins measured up to 3600 secs with time intervals of 60 secs by calcein accumulation as...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
9/12/2017
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL