BDBM50174460 (Z)-4-[1-(3-Cyano-benzyl)-1H-pyrrol-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL196397

SMILES OC(=O)C(=O)CC(=O)c1ccn(Cc2cccc(c2)C#N)c1

InChI Key InChIKey=SCUITMWZAYHKIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174460   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50174460((Z)-4-[1-(3-Cyano-benzyl)-1H-pyrrol-3-yl]-2-hydrox...)
Affinity DataIC50: 4.60E+3nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed