BDBM50174471 (Z)-4-[3-(2-Chloro-6-cyano-benzyloxy)-5-hydroxy-phenyl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL198423

SMILES OC(=O)C(=O)CC(=O)c1cc(O)cc(OCc2c(Cl)cccc2C#N)c1

InChI Key InChIKey=NYAVXGRYGRTUAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174471   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50174471((Z)-4-[3-(2-Chloro-6-cyano-benzyloxy)-5-hydroxy-ph...)
Affinity DataIC50: 100nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed