BDBM50174483 (Z)-2-Hydroxy-4-oxo-4-(5-piperidin-1-yl-thiophen-2-yl)-but-2-enoic acid::CHEMBL197033

SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)N1CCCCC1

InChI Key InChIKey=WUDJVFQOSNFAPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174483   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50174483((Z)-2-Hydroxy-4-oxo-4-(5-piperidin-1-yl-thiophen-2...)
Affinity DataIC50: 8.20E+3nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed