BDBM50174487 (Z)-4-[5-(3-Fluoro-benzyl)-1-methyl-1H-pyrrol-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL194572

SMILES Cn1cc(cc1Cc1cccc(F)c1)C(=O)CC(=O)C(O)=O

InChI Key InChIKey=CHSDSEGUOSPFRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174487   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50174487((Z)-4-[5-(3-Fluoro-benzyl)-1-methyl-1H-pyrrol-3-yl...)
Affinity DataIC50: 2.10E+4nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed