BDBM50174498 4-Adamantan-1-yl-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL196621

SMILES OC(=O)C(=O)CC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50174498   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50174498(4-Adamantan-1-yl-2-hydroxy-4-oxo-but-2-enoic acid ...)
Affinity DataIC50: 6.70E+3nMpH: 7.5Assay Description:Inhibitory concentration against NS5B HCV polymerase using [alpha-32P]UTP as radioligand (30 degree C for 2 h, at pH 7.5 with Tris-HCl buffer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed