BDBM50174542 (10aR,12aS)-7-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,9,10,10a,10b,11,12,12a-dodecahydro-4bH-1-oxa-chrysene-2,8-dione::CHEMBL197451

SMILES C[C@]12CCC3C(CCC4C(=O)C(=O)CC[C@]34C)C1CCC(=O)O2

InChI Key InChIKey=OQHKRXIIDQKKDS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174542   

TargetAromatase(Human)
University of Oporto

Curated by ChEMBL
LigandPNGBDBM50174542((10aR,12aS)-7-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,...)
Affinity DataKi:  660nMAssay Description:Inhibition constant against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAromatase(Human)
University of Oporto

Curated by ChEMBL
LigandPNGBDBM50174542((10aR,12aS)-7-Hydroxy-10a,12a-dimethyl-3,4,4a,5,6,...)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed