BDBM50174638 CHEMBL198325::{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-ylmethyl}-(4-nitro-phenyl)-amine

SMILES C[C@@H]1CCCN1CCc1cc2cc(CNc3ccc(cc3)[N+]([O-])=O)ccc2o1

InChI Key InChIKey=JUSSVZPDQWWYHB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174638   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174638({2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzof...)
Affinity DataKi:  0.740nMAssay Description:In vitro binding affinity for human histamine H3 receptor using [3H]N-alpha-methylhistamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174638({2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzof...)
Affinity DataKi:  2.12nMAssay Description:In vitro binding affinity for rat histamine H3 receptor using [3H]N-alpha-methylhistamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed