BDBM50174686 1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cyclohepten-8-yl)-3-(4-chloro-3-trifluoromethyl-phenyl)-urea::CHEMBL199886

SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3Oc4ncnc(Cl)c4N=Cc3c2)ccc1Cl

InChI Key InChIKey=RGGIEVPMRLEMRX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50174686   

TargetInsulin receptor(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174686(1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against IRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174686(1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 450nMAssay Description:Inhibitory activity against FLT3 kinase in a HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Imclone Systems

Curated by ChEMBL
LigandPNGBDBM50174686(1-(1-chloro-5-oxa-2,4,11-triaza-dibenzo[a,d]cycloh...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed