BDBM50174892 CHEMBL381013::N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)piperidin-4-yl)-5-nitro-1H-indazol-3-amine

SMILES [O-][N+](=O)c1ccc2[nH]nc(NC3CCN(Cc4ccc5OCCOc5c4)CC3)c2c1

InChI Key InChIKey=CVCGBWLRYBCWQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174892   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174892(N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)...)
Affinity DataIC50: 520nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174892(N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)...)
Affinity DataIC50: 30nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed