BDBM50174893 CHEMBL197497::N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-yl)-5-chloro-1-(pyridin-3-ylmethyl)-1H-indazol-3-amine

SMILES Clc1ccc2n(Cc3cccnc3)nc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1

InChI Key InChIKey=UIBIPJLWIWSEAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174893   

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174893(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174893(N-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50: 290nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed