BDBM50175400 CHEMBL201315::N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,4-triazol-3-yl)methyl)quinoline-2-carboxamide

SMILES Brc1ccc(CCN(Cc2nncn2Cc2ccc(cc2)C#N)C(=O)c2ccc3ccccc3n2)cc1

InChI Key InChIKey=HBICQBWDOZPTLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175400   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50175400(N-(4-bromophenethyl)-N-((4-(4-cyanobenzyl)-4H-1,2,...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against K-Ras farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed