BDBM50175516 CHEMBL372588::{11-[2-(4-Benzyl-piperidin-1-yl)-eth-(E)-ylidene]-6,11-dihydro-dibenzo[b,e]oxepin-2-yl}-acetic acid

SMILES OC(=O)Cc1ccc2OCc3ccccc3\C(=C\CN3CCC(Cc4ccccc4)CC3)c2c1

InChI Key InChIKey=PPABRKQHBMJESP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50175516   

TargetHistamine H1 receptor(Guinea pig)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50175516({11-[2-(4-Benzyl-piperidin-1-yl)-eth-(E)-ylidene]-...)
Affinity DataKi:  15nMAssay Description:Inhibition of the specific binding of [3H]pyrilamine to guinea pig cerebellum histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175516({11-[2-(4-Benzyl-piperidin-1-yl)-eth-(E)-ylidene]-...)
Affinity DataKi:  20nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50175516({11-[2-(4-Benzyl-piperidin-1-yl)-eth-(E)-ylidene]-...)
Affinity DataKi:  740nMAssay Description:Inhibition constant against thromboxane A2 receptor to prostaglandin H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed