BDBM50175705 3-((S)-2-(3-benzoyl-1-cyanoindolizin-5-yloxy)-4-methylpentanamido)-3-phenylpropanoic acid::CHEMBL372159

SMILES CC(C)C[C@H](Oc1cccc2c(cc(C(=O)c3ccccc3)n12)C#N)C(=O)NC(CC(O)=O)c1ccccc1

InChI Key InChIKey=ZRQNHCUCPHPESK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50175705   

TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175705(3-((S)-2-(3-benzoyl-1-cyanoindolizin-5-yloxy)-4-me...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against MPTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175705(3-((S)-2-(3-benzoyl-1-cyanoindolizin-5-yloxy)-4-me...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity against MPTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175705(3-((S)-2-(3-benzoyl-1-cyanoindolizin-5-yloxy)-4-me...)
Affinity DataIC50: 8.51E+4nMAssay Description:Inhibitory activity against PTP1bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175705(3-((S)-2-(3-benzoyl-1-cyanoindolizin-5-yloxy)-4-me...)
Affinity DataIC50: 7.07E+4nMAssay Description:Inhibitory activity against Cdc25A phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Technische UniversitäT MüNchen

Curated by ChEMBL
LigandPNGBDBM50175705(3-((S)-2-(3-benzoyl-1-cyanoindolizin-5-yloxy)-4-me...)
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibitory activity against VHR phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed