BDBM50175908 8-[(1S,2S)-2-(4-chloro-3-trifluoromethyl-phenyl)-cyclohexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL424845

SMILES FC(F)(F)c1cc(ccc1Cl)[C@@H]1CCCC[C@@H]1N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=YMDVHRSBNZMYOM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50175908   

TargetSodium- and chloride-dependent glycine transporter 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175908(8-[(1S,2S)-2-(4-chloro-3-trifluoromethyl-phenyl)-c...)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of [3H]glycine uptake in cells transfected with human GlyT1 cDNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed