BDBM50176115 (Z)-4-(1-Benzyl-5-methoxy-1H-indol-3-yl)-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL196689

SMILES COc1ccc2n(Cc3ccccc3)cc(C(=O)CC(=O)C(O)=O)c2c1

InChI Key InChIKey=USPINJVQBSDNLG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176115   

TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176115((Z)-4-(1-Benzyl-5-methoxy-1H-indol-3-yl)-2-hydroxy...)
Affinity DataIC50: 17nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176115((Z)-4-(1-Benzyl-5-methoxy-1H-indol-3-yl)-2-hydroxy...)
Affinity DataIC50: 21nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176115((Z)-4-(1-Benzyl-5-methoxy-1H-indol-3-yl)-2-hydroxy...)
Affinity DataIC50: 2.16E+3nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase 3' strand transferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed