BDBM50176702 (S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-10,15-dibenzyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexaaza-cyclodocos-4-yl}-3-(4-hydroxy-phenyl)-propionamide::CHEMBL200129

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O

InChI Key InChIKey=IVZGEIYAIJCDDR-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50176702   

TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50: 0.870nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50: 0.870nMAssay Description:Agonistic efficacy at human delta opioid receptor by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50: 0.200nMAssay Description:Agonistic efficacy at rat mu opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50: 9.90nMAssay Description:Activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50: 25nMAssay Description:Activity at mu opioid receptor in longitudinal muscle myenteric plexus from guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
D'Annunzio University of Chieti���Pescara

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]lleDelt2 from DOR in Wistar rat whole brain membranes after 45 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50176702((S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat whole brain membranes after 45 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed