BDBM50177491 CHEMBL205173::{(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-pentyl}-carbamic acid tert-butyl ester

SMILES CCCC[C@H](NC(=O)OC(C)(C)C)C=NNC(=O)N1CCOCC1

InChI Key InChIKey=LOTRMFMPZMRMGH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177491   

TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50177491({(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-p...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human cathepsin K in a fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50177491({(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-p...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human cathepsin L in a fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPro-cathepsin H(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50177491({(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-p...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human cathepsin H in a fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50177491({(S)-1-[(morpholine-4-carbonyl)-hydrazonomethyl]-p...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human cathepsin B in a fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed