BDBM50177720 CHEMBL3814090

SMILES Cn1cc(cn1)-c1ccc-2c(c1)C(=O)c1c-2[nH]c2cc(ccc12)C#N

InChI Key InChIKey=BOZUVHIZHDGLPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177720   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177720(CHEMBL3814090)
Affinity DataIC50: 83nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177720(CHEMBL3814090)
Affinity DataIC50: 97nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed