BDBM50177809 CHEMBL3814631

SMILES Nc1nc(NCc2ccc(Br)cc2)c2ccccc2n1

InChI Key InChIKey=ZUYRRDXUXPCRBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177809   

TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50177809(CHEMBL3814631)
Affinity DataIC50: 80nMAssay Description:Inhibition of self-induced amyloid beta 40 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50177809(CHEMBL3814631)
Affinity DataIC50: 80nMAssay Description:Inhibition of amyloid beta40 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50177809(CHEMBL3814631)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of amyloid beta42 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50177809(CHEMBL3814631)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of self-induced amyloid beta 42 (unknown origin) aggregation measured for 24 hrs by thioflavin T-based fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2017
Entry Details Article
PubMed