BDBM50178251 3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)thiazol-4-yl)butanoic acid::CHEMBL441122

SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(F)c(F)c1

InChI Key InChIKey=QCZXVUVLNOHNFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178251   

TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50: 3.49nMAssay Description:Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50: 484nMAssay Description:Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50178251(3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...)
Affinity DataIC50: 2.12E+3nMAssay Description:Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed