BDBM50178519 CHEMBL378592::N-(3,4-dimethoxyphenyl)-5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-1,3,4-oxadiazol-2-amine

SMILES COc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1OC

InChI Key InChIKey=QJNOSASLYRSGGR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178519   

TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178519(N-(3,4-dimethoxyphenyl)-5-(1-methyl-4-(pyridin-4-y...)
Affinity DataIC50: 52nMAssay Description:Inhibition of VEGFR2 by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178519(N-(3,4-dimethoxyphenyl)-5-(1-methyl-4-(pyridin-4-y...)
Affinity DataIC50: 93nMAssay Description:Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50178519(N-(3,4-dimethoxyphenyl)-5-(1-methyl-4-(pyridin-4-y...)
Affinity DataIC50: 590nMAssay Description:Inhibition of VEGFR1 by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed