BDBM50178571 CHEMBL204958::N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-o-tolylnicotinamide

SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1cnccc1-c1ccccc1C

InChI Key InChIKey=GTBUTLFXQOBLCG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50178571   

TargetSubstance-P receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50178571(N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-o-to...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]-labeled substance P from cloned human NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed