BDBM50178600 2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)methyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine::CHEMBL205031

SMILES C(C1CNc2ccccc2O1)N1CCC(=CC1)c1c[nH]c2ccccc12

InChI Key InChIKey=VSXPSCOXEGOPID-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178600   

Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178600(2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataEC50:  1.13E+3nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTP-gamma-S binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178600(2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataKi:  8.37nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178600(2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataKi:  805nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed