BDBM50178676 CHEMBL198641::[(3S,4R)-4-(4-chlorophenyl)-1-methylpiperidine-3-yl-methylsulfanyl]acetic acid methyl ester

SMILES COC(=O)CSC[C@@H]1CN(C)CC[C@H]1c1ccc(Cl)cc1

InChI Key InChIKey=IZICDKSTJHYQIZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178676   

TargetTransporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178676([(3S,4R)-4-(4-chlorophenyl)-1-methylpiperidine-3-y...)
Affinity DataKi:  57nMAssay Description:Ability to inhibit [3H]NE uptake through NET in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178676([(3S,4R)-4-(4-chlorophenyl)-1-methylpiperidine-3-y...)
Affinity DataKi:  69nMAssay Description:Ability to inhibit [3H]5-HT uptake through SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50178676([(3S,4R)-4-(4-chlorophenyl)-1-methylpiperidine-3-y...)
Affinity DataKi:  2.62E+3nMAssay Description:Ability to inhibit [3H]DA uptake through DAT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed