BDBM50178789 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxamide::CHEMBL173124

SMILES NC(=O)C1CCc2c(C1)[nH]c1ccc(Cl)cc21

InChI Key InChIKey=AAALFTUMOWSRRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50178789   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Elixir Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50178789(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxa...)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibitory activity against recombinant human SIRT1 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta sliding clamp(Escherichia coli (strain K12))
The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50178789(6-chloro-2,3,4,9-tetrahydro-1H-carbazole-2-carboxa...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2016
Entry Details Article
PubMed