BDBM50179459 (S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid ((S)-1-methylcarbamoyl-2-naphthalen-2-yl-ethyl)-amide::Ac-Tyr-D-Phe-Arg-2-Nal-NHCH3::CHEMBL202699

SMILES [#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc2ccccc2c1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](-[#6])=O

InChI Key InChIKey=FLWDSNSPKOPGSI-UHFFFAOYSA-N

Data  9 KI  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50179459   

TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human MC1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human MC3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human MC3R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at human MC1R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  44nMAssay Description:Agonist potency at MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at human MC4R transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  104nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  104nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  104nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.73E+3nMAssay Description:Binding affinity to human MC3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.73E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.73E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  4.52E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  4.52E+3nMAssay Description:Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  4.52E+3nMAssay Description:Binding affinity to human MC1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed