BDBM50179642 1-(3-chlorophenyl)-3-(1-ethyl-5-methyl-4-oxoimidazolidin-2-ylidene)urea::CHEMBL202845

SMILES CCn1c(C)c(O)nc1NC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=YUEORBSSOODDSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179642   

TargetMetabotropic glutamate receptor 5(Rat)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179642(1-(3-chlorophenyl)-3-(1-ethyl-5-methyl-4-oxoimidaz...)
Affinity DataIC50: 320nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179642(1-(3-chlorophenyl)-3-(1-ethyl-5-methyl-4-oxoimidaz...)
Affinity DataIC50: 410nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed