BDBM50179671 (2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-benzyl)-1H-indol-4-yloxy]-tetrahydro-pyran-3,4,5-triol::CHEMBL203953

SMILES Cc1ccc(Cc2c[nH]c3cccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c23)cc1

InChI Key InChIKey=RPTIPWSUINVZPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179671   

TargetSodium/glucose cotransporter 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179671((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-be...)
Affinity DataIC50: 66nMAssay Description:Inhibitory activity against SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50179671((2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-[3-(4-methyl-be...)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibitory activity against SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed