BDBM50180016 (S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)-3-(1H-indol-3-yl)propanoic acid::CHEMBL199917

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)CS(=O)(=O)c1ccc(NC(=O)c2ccc(Br)cc2)cc1

InChI Key InChIKey=GJITXIQQHBXCIH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50180016   

TargetMatrix metalloproteinase-9(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180016((S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)...)
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180016((S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180016((S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180016((S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180016((S)-2-((4-(4-bromobenzamido)phenylsulfonyl)methyl)...)
Affinity DataIC50: 2.60nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed