BDBM50180252 (2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine::(S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine::CHEMBL199775

SMILES COc1ccc2cnn(C[C@H](C)N)c2c1

InChI Key InChIKey=WSEWULCWBQDNEH-UHFFFAOYSA-N

Data  5 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50180252   

Target5-hydroxytryptamine receptor 2A(Rat)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataEC50:  54nMAssay Description:Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataEC50:  6.70nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataEC50:  4.20nMAssay Description:Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]5-HT from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]5-HT from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed