BDBM50180551 2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL377091

SMILES Cn1nnc(C2(F)CC3(c4ccccc4)NC2CCC3OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1

InChI Key InChIKey=UZFWWSXEIJUCEB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180551   

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180551BDBM50180551(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]-labeled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180551BDBM50180551(2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [35S]-labeled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed