BDBM50180554 2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-6-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane::CHEMBL379152

SMILES O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)NC1CCC2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1

InChI Key InChIKey=MXKZKTBJVYCBDH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180554   

TargetSubstance-P receptor(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180554BDBM50180554(2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-6-(...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]-labeled substance P from human cloned NK1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180554BDBM50180554(2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-6-(...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [35S]-labeled MK499 from cloned hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed