BDBM50180636 CHEMBL3813725

SMILES OC(=O)c1ccc2occ(\C=N\Nc3nc4CCSCc4c(n3)N3CCOCC3)c(=O)c2c1

InChI Key InChIKey=MZFQJTVJGDZHMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50180636   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50180636(CHEMBL3813725)
Affinity DataIC50: 920nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PI substrate incubated for 60 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50180636(CHEMBL3813725)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of mTOR (unknown origin) using ULight4E-BP1 peptide as substrate incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed