BDBM50181135 CHEMBL206249::rac-4-(2,5-difluorophenyl)-2-(3-hydroxyphenyl)-N-methyl-N-(piperidin-4-yl)-2H-pyrrole-1(5H)-carboxamide

SMILES CN(C1CCNCC1)C(=O)N1CC(=CC1c1cccc(O)c1)c1cc(F)ccc1F

InChI Key InChIKey=XYUMIRJLHXWAGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181135   

TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50181135(rac-4-(2,5-difluorophenyl)-2-(3-hydroxyphenyl)-N-m...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of KSP by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50181135(rac-4-(2,5-difluorophenyl)-2-(3-hydroxyphenyl)-N-m...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory activity against human hERG receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed