BDBM50181374 2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-piperidine)-1-ylpropyl]benzamide::CHEMBL202443

SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1ccccc1Oc1ccccc1

InChI Key InChIKey=KFXRFKRUMZXDFI-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50181374   

TargetDelta-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50181374(2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]naltrindole from cloned human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50181374(2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity on nociceptin-induced [35S]GTP-gamma-S binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50181374(2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...)
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50181374(2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]diprenorphin from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50181374(2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity on nociceptin-induced maximal [35S]GTP-gamma-S binding to ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50181374(2-phenoxy-N-[3-spiro(2,3-dihydro-1H-indene-1,4'-pi...)
Affinity DataIC50: 9.60E+3nMAssay Description:Displacement of [3H]U-69593 from cloned human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed