BDBM50182758 CHEMBL3819243

SMILES Fc1cc(ccc1Cl)[C@@H]1OCCNC[C@H]1Cn1ncccc1=O

InChI Key InChIKey=VZYAMIGSWLJHCX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182758   

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182758(CHEMBL3819243)
Affinity DataIC50: 0.0650nMAssay Description:Inhibition of human NET expressed in CHO cells assessed as [3H]-Norepinephrine reuptake incubated for 45 mins measured after 30 mins by topcount meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182758(CHEMBL3819243)
Affinity DataIC50: 79nMAssay Description:Inhibition of human SERT expressed in CHO cells assessed as [3H]-5-hydroxytryptamine reuptake incubated for 20 mins measured after 30 mins by topcoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50182758(CHEMBL3819243)
Affinity DataIC50: 240nMAssay Description:Inhibition of human DAT expressed in CHO cells assessed as [3H]-dopamine reuptake incubated for 60 mins measured after 30 mins by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2017
Entry Details Article
PubMed