BDBM50183494 2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-thienyl]-5,6-dihydroxy-pyrimidine-4-carboxylic acid::CHEMBL205990
SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)OCc1c(Cl)cccc1Cl
InChI Key InChIKey=SBPHTZDKEFBAPI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50183494
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
P. Angeletti S.P.A. (Merck Research Laboratories)
Curated by ChEMBL
P. Angeletti S.P.A. (Merck Research Laboratories)
Curated by ChEMBL
Affinity DataEC50: 1.86E+4nMAssay Description:Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymeraseMore data for this Ligand-Target Pair
Affinity DataIC50: 258nMAssay Description:Displacement of 0.1 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Displacement of 1 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of 5 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 174nMAssay Description:Displacement of 50 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 302nMAssay Description:Displacement of 100 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 882nMAssay Description:Displacement of 500 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of NS5B-mediated RNA synthesis in Hepatitis C virus assessed as decrease in formation of full-length product after 45 minsMore data for this Ligand-Target Pair
