BDBM50183537 (S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fluorophenyl)-methoxy]ethyl]piperidine dioxalate::CHEMBL381842

SMILES N[C@H](CN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=YGBCDXIPWNLLEI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50183537   

TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]DA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  76nMAssay Description:Displacement of [125I]RTI-55 from SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  228nMAssay Description:Inhibition of [3H]5-HT uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  338nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50183537((S)-(+)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  851nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed