BDBM50184251 4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)benzoic acid::CHEMBL207142

SMILES CCCc1c(OCCCN(C)c2ccc(cc2)C(O)=O)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=PNGBFYGVOOVAIY-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50184251   

TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184251(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]i...)
Affinity DataIC50: 190nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184251(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]i...)
Affinity DataEC50:  6.00E+3nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184251(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]i...)
Affinity DataEC50:  5.10E+3nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184251(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]i...)
Affinity DataIC50: 79nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed