BDBM50184257 2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indolin-5-yl)acetic acid::CHEMBL207690

SMILES CCCc1c(OCCCN2C(=O)Cc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F

InChI Key InChIKey=WRGYDZSMTYBYJC-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184257   

TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184257(2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LXR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184257(2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d...)
Affinity DataEC50:  180nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184257(2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d...)
Affinity DataEC50:  140nMAssay Description:Activity at LXR beta as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184257(2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184257(2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d...)
Affinity DataIC50: 19nMAssay Description:Activity at LXR alpha as beta-lactamase transactivation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50184257(2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed