BDBM50184348 (Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)-4-oxo-1,4-dihydro-quinolin-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid ethyl ester::CHEMBL383505

SMILES CCOC(=O)C(=O)CC(=O)c1ccc2ncc(C(=O)CC(=O)C(=O)OCC)c(O)c2c1

InChI Key InChIKey=NIRYNRRPKOPAKY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50184348   

TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50184348((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity in presence of MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50184348((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by gel-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50184348((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MgCl2 by plate-based electrochemiluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50184348((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activity in presence of MnCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50184348((Z)-4-[6-((Z)-3-ethoxycarbonyl-3-hydroxy-acryloyl)...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity in presence of MnCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed