BDBM50184652 CHEMBL210469::[4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphenyl-5'-ylmethoxy)-2-methyl-phenoxy]-acetic acid

SMILES Cc1cc(OCc2cc(cc(c2)-c2ccc(cc2)C(F)(F)F)-c2ccc(cc2)C(F)(F)F)ccc1OCC(O)=O

InChI Key InChIKey=ZKICTBITKAPJOB-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184652   

TargetPeroxisome proliferator-activated receptor alpha(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50184652([4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphen...)
Affinity DataEC50:  3.33E+3nMAssay Description:Effect on human PPARalpha transactivation in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50184652([4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphen...)
Affinity DataEC50:  10nMAssay Description:Effect on human PPARdelta transactivation in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50184652([4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphen...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on human PPARgamma transactivation in 293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50184652([4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphen...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50184652([4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphen...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50184652([4-(4,4''-Bis-trifluoromethyl-[1,1';3',1'']terphen...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells co-transfected with Gal4-DBD by luciferase transactivation as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed