BDBM50184812 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-(2-(1-methylpiperidin-4-yl)ethoxy)pyrrolo[1,2-f][1,2,4]triazine::CHEMBL206145

SMILES CN1CCC(CCOc2cn3ncnc(Oc4ccc5[nH]c(C)cc5c4F)c3c2C)CC1

InChI Key InChIKey=DGPAWMWBQNMPFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50184812   

TargetCytochrome P450 3A4(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184812(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50184812(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methyl-6-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed