BDBM50185336 5-[4-fluoro-3-(3-fluoropyridin-2-yl)phenyl]-3-(2-fluorophenyl)-pyridazine::CHEMBL206479

SMILES Fc1ccccc1-c1cc(cnn1)-c1ccc(F)c(c1)-c1ncccc1F

InChI Key InChIKey=UJBOQYCZTOTBAN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185336   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185336(5-[4-fluoro-3-(3-fluoropyridin-2-yl)phenyl]-3-(2-f...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]Ro-151788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185336(5-[4-fluoro-3-(3-fluoropyridin-2-yl)phenyl]-3-(2-f...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]Ro-151788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed