BDBM50185346 1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-6-carboxylic acid::1-[3-(4-octylphenoxy)-2-oxopropyl]indole-6-carboxylic acid::CHEMBL205941

SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3ccc(cc23)C(O)=O)cc1

InChI Key InChIKey=YRYOEVQZRFTJRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185346   

TargetCytosolic phospholipase A2(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185346(1-[3-(4-octylphenoxy)-2-oxopropyl]indole-6-carboxy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cPLA2 from human platelets by RP-HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCytosolic phospholipase A2(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185346(1-[3-(4-octylphenoxy)-2-oxopropyl]indole-6-carboxy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of cPLA2 in human platelets assessed as arachidonic acid releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetCytosolic phospholipase A2(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185346(1-[3-(4-octylphenoxy)-2-oxopropyl]indole-6-carboxy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human isolated cPLA2-alpha by vesicle assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytosolic phospholipase A2(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185346(1-[3-(4-octylphenoxy)-2-oxopropyl]indole-6-carboxy...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human plateletMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed