BDBM50185528 2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)phenyl)pyrrolidin-3-yl)acetic acid::CHEMBL377855

SMILES OC(=O)CC1CNC(C1)c1ccc(OCc2cc(c(s2)C(F)(F)F)-c2ccccc2)cc1

InChI Key InChIKey=UNTMCOZQSGVJBE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185528   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185528(2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-y...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [33P]S1P from human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185528(2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-y...)
Affinity DataIC50: 390nMAssay Description:Displacement of [33P]S1P from human S1P4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185528(2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-y...)
Affinity DataIC50: 390nMAssay Description:Displacement of [33P]S1P from human S1P5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185528(2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-y...)
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [33P]S1P from human S1P3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50185528(2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-y...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [33P]S1P from human S1P2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed